Best Infant Formulas For Newborns in 2025

Once a niche product, J.P. Holle Organic Infant Formula Stage 1 has become a gold standard for parents seeking a European-inspired organic option. Known for its minimal processing and high-quality organic ingredients, it aims to mimic breast milk as closely as possible. It features organic skim milk, organic vegetable oils, and lactose as the primary carbohydrate, avoiding corn syrup solids. This formula is suitable from birth and is often lauded for being gentle on sensitive newborn tummies due to its simple, clean ingredient list. Its focus on natural, biodynamic farming practices for its ingredients sets it apart, appealing to parents prioritizing purity.

Similac 360 Total Care Infant Formula is a cutting-edge option that aims to provide comprehensive nutrition for newborns. Its standout feature is its blend of five different human milk oligosaccharides (HMOs), which are prebiotics naturally found in breast milk. These HMOs support the immune system and promote a healthy gut microbiome, bringing formula nutrition closer to that of breast milk. It also includes DHA, Lutein, and Vitamin E for brain and eye development. This formula is designed for everyday feeding of healthy, full-term infants and addresses all three primary selection criteria by providing complete nutrition, quality ingredients (with the notable exception of corn syrup solids for some parents), and support for digestive health through its HMO blend.

Enfamil NeuroPro Gentlease Infant Formula is specifically designed for babies with fussiness, gas, and crying, often associated with a sensitive digestive system. It features a partially hydrolyzed protein, meaning the proteins are already broken down into smaller pieces, making them easier for a newborn's immature digestive system to process. This significantly aids in digestibility and reduces common feeding issues. Beyond its gentle nature, NeuroPro Gentlease provides DHA and ARA for brain development and is formulated to be nutritionally complete. It meets the criteria of excellent digestibility while still providing high-quality, complete nutrition. Its widespread availability and proven track record make it a go-to choice for parents facing common mild digestive discomforts in their newborns.

Gerber Good Start Soy Plant-Based Protein Powder Infant Formula is an excellent option for newborns whose parents prefer a plant-based diet or for those who cannot tolerate cow's milk proteins. It is made with non-GMO soy protein and contains DHA for brain and eye development, along with a blend of nutrients to ensure complete infant nutrition. This formula avoids lactose, making it suitable for babies with lactose intolerance or galactosemia. While soy as a primary milk alternative source can be debated, for specific cases where cow's milk is not an option, this formula provides a nutritionally sound and digestible solution. Its plant-based nature addresses a distinct need in the market, aligning with both dietary preferences and specific medical requirements.

Kendamil Organic First Infant Milk is a standout British-made formula that emphasizes natural, whole milk as its primary base, rather than skimmed milk. This approach aims to replicate the fat profile found in breast milk more closely. It's certified organic, non-GMO, and free from palm oil, fish oil, and soy, which are common concerns for many parents. Instead, it uses plant-based DHA derived from algae, making it a potentially more sustainable and allergen-friendly choice for some. Its commitment to transparent, high-quality, and sustainably sourced ingredients makes it an attractive option for environmentally conscious parents who also prioritize gentle digestibility and complete nutrition for their newborns.